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Insulin cream offers needle-free option for diabetes

By Eric November 20, 2025

In a groundbreaking study published in *Nature*, researchers have developed a skin-permeable polymer that demonstrates significant potential for insulin delivery in animal models. This innovative approach could revolutionize diabetes management by providing a non-invasive method for insulin administration, which is traditionally delivered through injections. The polymer works by forming a thin, flexible film that adheres to the skin, allowing insulin molecules to penetrate through the skin barrier and enter the bloodstream. The study’s results indicate that this method not only maintains stable insulin levels but also reduces the risk of hypoglycemia, a common concern for individuals managing diabetes.

The implications of this research extend beyond diabetes treatment. The polymer’s ability to facilitate drug delivery through the skin opens up new avenues for administering various medications, potentially improving patient compliance and comfort. For instance, chronic conditions that require regular medication could benefit from this technology, reducing the need for frequent injections or oral medications that can be difficult for some patients to manage. As the research progresses, further studies will aim to assess the long-term efficacy and safety of this delivery system in humans, with the hope of bringing this innovative solution to market in the near future.

In addition to advancements in diabetes care, the same issue of *Nature* also explores how the brain processes unfamiliar languages. Researchers have found that exposure to languages that differ significantly from one’s native tongue activates specific neural pathways, suggesting that the brain adapts and reorganizes itself to accommodate new linguistic structures. This finding underscores the brain’s remarkable plasticity and its capacity to learn and adapt throughout an individual’s life. Understanding these mechanisms could have profound implications for language learning and cognitive development, offering insights into how individuals can be better supported in acquiring new languages, especially in an increasingly globalized world. Together, these studies highlight the dynamic interplay between innovative medical technologies and our understanding of cognitive processes, paving the way for future research and applications in both fields.

https://www.youtube.com/watch?v=iv1Hqlp1enk

Nature, Published online: 19 November 2025;
doi:10.1038/d41586-025-03803-0
Skin-permeable polymer shows promise at insulin delivery in animal experiments — plus, how the brain responds to unfamiliar languages.

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