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A 13-year-old dies after participating in a Benadryl TikTok ‘challenge’

By Eric November 18, 2025

A tragic incident in Ohio has highlighted the perilous nature of social media challenges, as a 13-year-old boy lost his life after attempting a dangerous TikTok challenge involving the consumption of large quantities of Benadryl. Reports indicate that the boy, identified as Jacob, ingested an excessive amount of the over-the-counter antihistamine in an effort to participate in a trend that has gained notoriety on TikTok, where users are encouraged to document their experiences with various substances. This incident not only underscores the risks associated with viral online challenges but also raises concerns about the influence of social media on youth behavior.

The challenge, which encourages participants to take Benadryl to induce hallucinations, has been met with warnings from health professionals regarding its potentially fatal consequences. Overdose symptoms can include severe respiratory issues, seizures, and even death, particularly in adolescents whose bodies are still developing. Jacob’s family has since created a GoFundMe account to cover funeral expenses, expressing their devastation and urging other parents to talk to their children about the dangers of such challenges. The emotional toll on the family is profound, as they navigate their grief while also advocating for awareness about the risks associated with social media trends.

This heartbreaking event serves as a stark reminder of the responsibilities that come with social media use, particularly among younger audiences. Experts emphasize the importance of open communication between parents and children about the dangers of participating in risky online challenges. As social media platforms continue to evolve, so too must the strategies for educating young users about the potential consequences of their actions. Jacob’s story is a call to action for parents, educators, and social media platforms alike to work together in fostering a safer online environment for children.

A 13-year-old in Ohio has died after “he took a bunch of Benadryl,” trying a dangerous TikTok challenge that’s circulating online, according to a CNN affiliate and a GoFundMe account from his family.

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