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Sponging away phylogenomic incongruence | Science

By Eric November 16, 2025

Recent research has provided compelling evidence suggesting that sponges may be the most distant animal relatives of humans, challenging long-held assumptions about the evolutionary tree of life. A team of scientists conducted a comprehensive analysis of genetic data from various animal species, focusing on genes that exhibit strong and consistent signals across multiple lineages. Their findings indicate that sponges, which are simple multicellular organisms, share a more ancient lineage with humans than previously thought, potentially reshaping our understanding of animal evolution.

The study utilized advanced genomic techniques to analyze the DNA sequences of numerous species, including sponges, jellyfish, and other invertebrates. The researchers identified specific genes that are highly conserved and show significant similarity between sponges and more complex animals, including humans. This genetic evidence suggests that sponges diverged from the common ancestor of all animals much earlier than other groups, positioning them as a critical point of reference in the evolutionary history. For instance, the analysis highlighted genes responsible for fundamental biological processes, such as cell signaling and immune responses, that are remarkably similar between sponges and humans, underscoring the deep evolutionary connections that exist.

This revelation has far-reaching implications for our understanding of biodiversity and evolutionary biology. It suggests that the traits and characteristics we often associate with more complex animals, including humans, may have their roots in the simple biology of sponges. By studying these ancient organisms, scientists can gain insights into the fundamental mechanisms of life and the evolutionary processes that have shaped the animal kingdom over millions of years. As research continues to unfold, the relationship between sponges and humans may provide new perspectives on how early life forms adapted to their environments, ultimately leading to the vast array of species we see today. This study not only highlights the importance of sponges in the evolutionary narrative but also opens new avenues for exploration in the fields of genetics and evolutionary development.

Genes with strong and consistent signals favor sponges as humans’ most distant animal relatives

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