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Health

Alzheimer’s Is One Form of Dementia. Here’s What to Know About the Others.

By Eric December 6, 2025

In recent discussions surrounding brain health, the focus has often been on the most well-known types of substances that impact cognitive function and mental well-being. However, it’s crucial to expand our understanding to include other main types of substances that can significantly affect the brain. These include alcohol, caffeine, nicotine, and various recreational drugs, each of which interacts with the brain’s chemistry in unique ways, influencing mood, cognition, and overall mental health.

Alcohol, for instance, is a depressant that can lead to short-term euphoria but often results in impaired judgment and coordination. Chronic use can lead to long-term changes in brain structure and function, particularly affecting areas responsible for memory and decision-making. Research indicates that heavy drinking can shrink the brain, leading to cognitive deficits and increased risk of dementia. On the other hand, caffeine, a stimulant found in coffee and tea, enhances alertness and concentration by blocking adenosine receptors, which can lead to increased productivity. However, excessive caffeine consumption can lead to anxiety and sleep disturbances, illustrating the delicate balance between its benefits and potential drawbacks.

Nicotine, commonly associated with tobacco products, has a complex relationship with the brain. While it can enhance focus and attention in the short term, its highly addictive nature poses significant risks, including long-term cognitive decline and increased susceptibility to mental health disorders. Recreational drugs, such as marijuana and cocaine, further complicate this landscape. Marijuana can alter mood and perception, and while some studies suggest potential therapeutic benefits, its long-term use can impair memory and learning. Cocaine, a powerful stimulant, can lead to intense euphoria but is also associated with severe psychological and physical health risks, including addiction and cardiovascular issues. Understanding these substances and their effects is vital for promoting brain health and making informed choices about their use.

Here’s what to know about the other main types and how they affect the brain.

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