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US appeals court to weigh reviving cases over Tylenol and autism

By Eric November 18, 2025

In a significant legal development, a U.S. appeals court is set to hear arguments from families advocating for the revival of their lawsuits against the manufacturers of Tylenol, officially known as acetaminophen. These lawsuits allege a potential link between the use of Tylenol during pregnancy and the development of autism in children. This case has gained traction after the Trump administration notably endorsed research suggesting that the pain reliever may contribute to autism risk, thereby amplifying public concern and prompting families to seek justice for their affected children.

The context surrounding this legal battle is rooted in ongoing debates about the safety of acetaminophen, particularly during pregnancy. While Tylenol is widely regarded as a safe over-the-counter medication for pain relief, emerging studies have raised questions about its long-term effects on fetal development. Families argue that they were not adequately warned about these risks, leading to their decision to file lawsuits against major pharmaceutical companies. The appeals court’s decision to hear these arguments could have significant implications, not only for the families involved but also for the pharmaceutical industry and public health policies regarding medication use during pregnancy.

As the court prepares to hear the case, experts and advocates are closely monitoring the proceedings, recognizing the potential for this ruling to influence future litigation and regulatory actions. The outcome may set a precedent for how similar claims are handled in the future, especially as more research continues to emerge on the effects of common medications during pregnancy. With public health implications at stake, the court’s decision could reshape the landscape of maternal health and medication safety, making it a pivotal moment for families and healthcare providers alike.

A U.S. appeals court is expected to hear arguments on Monday from families seeking to revive their lawsuits over Tylenol, after the Trump administration publicly promoted its claims that the popular painkiller is linked to autism in children.

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