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This mosquito death trap is all-natural and very deadly

By Eric November 9, 2025

In a groundbreaking study recently published in *Nature Microbiology*, researchers have harnessed the power of fungi to create a new, innovative solution to combat the deadly threat of mosquito-borne diseases. With diseases like malaria and dengue claiming over 500,000 lives in 2023 alone, the need for effective mosquito control has never been more urgent. Traditional chemical pesticides have become less effective as mosquitoes have developed resistance, prompting scientists to explore natural alternatives. Enter *Metarhizium*, a fungus that, when engineered to emit a sweet floral scent, can lure mosquitoes to their demise by deactivating their sperm and ultimately killing them.

This newly engineered strain of *Metarhizium* uses a compound called longifolene, a natural chemical found in many flowers, to attract mosquitoes. The researchers discovered that by enhancing the fungus’s ability to produce longifolene, they could significantly increase its effectiveness in drawing mosquitoes in. Once the mosquitoes encounter the fungus, they become infected and die within days—a process that was shown to be remarkably effective in lab tests, killing 90 to 100 percent of mosquitoes, even in environments where they had to compete with the scents of humans and real flowers. Unlike traditional pesticides, this fungus poses no harm to humans and breaks down naturally in the environment, making it a safer alternative for mosquito control.

The implications of this research are particularly significant for poorer regions in the global south, where mosquito-borne diseases are expected to rise due to climate change. The affordability and simplicity of using *Metarhizium*—which can be deployed using inexpensive materials like chicken droppings and rice husks—could drastically reduce disease-related deaths. The research team is now working on larger-scale outdoor trials to gain regulatory approval for this method. As Raymond St. Leger, a co-author of the study, emphasizes, this approach is not a one-size-fits-all solution, but rather a diverse toolkit that can be adapted to various environments and mosquito species. By providing communities with multiple options for mosquito control, the hope is to save countless lives and mitigate the impact of these deadly diseases.

https://www.youtube.com/watch?v=ksCGH1HZOh8

Never underestimate the power of
fungi
. It can turn
ants into “zombies,”
help fictional plumbers
grow
, and even look like
creepy fingers
. One newly engineered strain of fungus uses the power of smell to kill Earth’s
deadliest animal
—mosquitoes.

Mosquito-borne diseases, including malaria and dengue, kill thousands of people per year. In 2023 alone, malaria killed
over 500,000 people in 83 countries
. These illnesses are often difficult to control, and
mosquitoes
have gotten better at
resisting chemical pesticides
that used to work. 

However,
fighting nature with nature
could be one solution. A fungus called
Metarhizium
can be used to
deactivate mosquito sperm
, keeping the deadly ones from spreading disease. It may also help catch and kill the deadly insects.

Since mosquitoes are drawn to flowers, a team of researchers created a new strain of the
Metarhizium
fungus that imitates a flower’s sweet scent. That natural aroma comes from a chemical called longifolene in many types of flowers. The lab-grown fungus in this study essentially uses the longifolene to lure the bloodsucking mosquitoes to their deaths and is described in a
study recently published in the journal
Nature Microbiology
.

“Mosquitoes need flowers because they provide nectar, a crucial source of food for them, and they are drawn to flowers through their scents,”
Raymond St. Leger, a study co-author and entomologist at the University of Maryland, said in a statement

“After observing that some types of fungi could trick mosquitoes into thinking they were flowers, we realized we could turbo-charge the attraction by engineering fungi to produce more longifolene, a sweet-smelling compound that’s already very common in nature,” St. Leger said. “Before this study, longifolene wasn’t known to attract mosquitoes. We’re letting nature give us a hint to tell us what works against mosquitoes.” 

Once the fungus spores are put into a container, the
longifolene
chemicals are released instantly. They can be effective for months because they also come out gradually and not in one initial burst.  

Mosquitoes placed in a container.
Image: Mark Sherwood and Raymond St. Leger.

As soon as the mosquitoes encounter the fungus, they become infected and die within a few days. In lab tests, the fungus
killed 90 to 100 percent of mosquitoes
, even when it was placed in a large room and had to compete with the scents of humans and real flowers. While this fragrant fungus is deadly to mosquitoes, it does not hurt humans. Longiflorine is actually commonly used in perfumes. 

“This makes it much safer than many chemical pesticides. We’ve also designed the fungus and its containers to target mosquitoes specifically rather than any other insects and longifolene breaks down naturally in the environment,” said St. Leger.

Using a natural alternative like this fungus may also make it difficult or impossible for mosquitoes to outsmart or avoid, as they have with chemical alternatives. 

“If mosquitoes evolve to avoid longifolene, that could mean they’ll stop responding to flowers,” St. Leger explained. “But they need flowers as a food source to survive, so it would be very interesting to see how they could possibly avoid the fungus yet still be attracted to the flowers they need. It’ll be very difficult for them to overcome that hurdle, and we have the option of engineering the fungus to produce additional floral odors if they evolve to specifically avoid longifolene.”

Other
forms of
Metarhizium
are already used around the world
to ward off mosquitoes on cheap materials such as chicken droppings, rice husks, and wheat scraps. The affordability and simplicity of the fungus could be key to reducing mosquito disease-related deaths in many parts of the world, particularly in poorer regions in the global south where mosquito-borne diseases are expected to rise due to
climate change
. The same diseases that are currently limited to tropical regions could also begin to
threaten other places
due to rising global temperatures.

The team from this study is currently working on larger-scale outdoor trials of the new mosquito control method to submit for regulatory approval. 

“It’s not as if you’re going to necessarily find a silver bullet to control mosquitoes everywhere, but we’re trying to develop a very diverse and flexible set of tools that people in different parts of the world can use and choose from,” St. Leger said. “Different people will find different approaches work best for their particular situation and the particular mosquitoes they’re dealing with. In the end, our goal is to give people as many options as possible to save lives.”

The post
This mosquito death trap is all-natural and very deadly
appeared first on
Popular Science
.

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