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Health

Drug With a 30-Year Monopoly Is Target of State-Level Push to Curb Prices

By Eric October 27, 2025

Enbrel, a biologic medication primarily used to treat autoimmune conditions such as rheumatoid arthritis, psoriasis, and ankylosing spondylitis, has been a cornerstone in the management of these chronic diseases since its introduction nearly 30 years ago. Developed by Amgen and Wyeth (now part of Pfizer), Enbrel works by inhibiting tumor necrosis factor (TNF), a substance in the body that leads to inflammation and is often elevated in autoimmune disorders. By blocking TNF, Enbrel helps reduce inflammation, alleviate pain, and improve the overall quality of life for patients suffering from these debilitating conditions.

Over the decades, Enbrel has gained widespread recognition for its efficacy and has become a standard treatment option. Patients typically administer the medication through a once-a-week injection, making it a convenient choice for those managing chronic conditions. The drug has been instrumental in helping patients achieve remission and maintain functional ability, allowing many to resume normal activities. However, the journey of Enbrel is not without its controversies, particularly concerning its pricing and accessibility. As a biologic drug, Enbrel comes with a hefty price tag, which has raised concerns about affordability and insurance coverage for patients who need it most. The ongoing discussions around drug pricing in the United States have put Enbrel in the spotlight, prompting debates on the balance between innovation in drug development and the financial burden placed on patients.

As Enbrel approaches its 30th anniversary, the conversation surrounding its impact continues to evolve. While it has undoubtedly changed the landscape of treatment for autoimmune diseases, the challenges of affordability and access remain critical issues. Patients and healthcare providers alike are advocating for more transparent pricing models and better insurance coverage to ensure that life-changing medications like Enbrel remain accessible to those in need. As the healthcare industry grapples with these challenges, Enbrel’s legacy as a pioneering treatment will likely influence future discussions on drug development, pricing, and patient care in the realm of autoimmune diseases.

Related articles:
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Enbrel, a once-a-week injection used to treat a variety of autoimmune conditions, first arrived on the market nearly 30 years ago.

E

Eric

Eric is a seasoned journalist covering Health news.

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