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CEOs of Wells Fargo and Pfizer caution the U.S. could lose its edge to China without innovation

By Eric October 22, 2025

At CNBC’s recent Invest in America Forum, a panel of influential CEOs gathered to discuss the current state of the U.S. economy and the challenges it faces amid global competition. While the executives acknowledged that the United States continues to lead in several key sectors, they expressed concern over inconsistent policy frameworks and chronic underinvestment that threaten to undermine this competitive edge. The discussion highlighted how these factors are contributing to a gradual erosion of the U.S.’s dominance in critical industries such as technology, manufacturing, and clean energy.

The CEOs pointed out that while the U.S. remains a global leader in innovation and entrepreneurship, the lack of a cohesive and forward-thinking policy approach is creating uncertainty for businesses. For instance, the fluctuating regulatory environment around technology and energy sectors has made it difficult for companies to plan for the future or invest in long-term projects. This uncertainty is compounded by a noticeable decline in public and private investment in infrastructure and research and development, which are vital for maintaining the country’s competitive stance. The executives underscored the importance of strategic investments in areas like renewable energy and advanced manufacturing to ensure that the U.S. not only retains its leadership but also adapts to the rapidly changing global landscape.

In light of these challenges, the CEOs urged policymakers to prioritize a more consistent and supportive investment climate. They emphasized that the U.S. must harness its strengths in innovation and talent to foster growth and resilience. For example, they cited the potential of green technology and artificial intelligence as areas where the U.S. can lead if given the right support. The forum served as a call to action for both the private and public sectors to work collaboratively in addressing these issues, ensuring that America remains at the forefront of global economic leadership. As the conversation continues, the need for strategic investments and policies that encourage growth and innovation has never been more critical.

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Speaking at CNBC’s Invest in America Forum, the CEOs said the U.S. still leads in many sectors, but inconsistent policy and underinvestment is ceding ground.

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